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Enzymatic glucose fiber sensor for glucose concentration measurement with a heterodyne interferometry

類別:期刊論文

學年 / 學期:111-2

出版日期:2023-03-09 00:00:00

著者:Cheng-Chih Hsu; Wan-Yu Chung; Chun-Yi Chang; Chyan-Chyi Wu; Cheng-Ling Lee

著錄名稱、卷期、頁數:Sensors 23(6), p.2990

摘要:In this study, we developed a glucose fiber sensor incorporating heterodyne interferometry to measure the phase difference produced by the chemical reaction between glucose and glucose oxidase (GOx). Both theoretical and experimental results showed that the amount of phase variation is inversely proportional to glucose concentration. The proposed method provided a linear measurement range of the glucose concentration from 10 mg/dL to 550 mg/dL. The experimental results indicated that the sensitivity is proportional to the length of the enzymatic glucose sensor, and the optimum resolution can be obtained at a sensor length of 3 cm. The optimum resolution of the proposed method is better than 0.6 mg/dL. Moreover, the proposed sensor demonstrates good repeatability and reliability. The average relative standard deviation (RSD) is better than 10% and satisfied the minimum requirement for point-of-care devices.

關鍵字:enzymatic glucose sensor; no-core fiber; heterodyne interferometry

語言:en

ISSN:1424-8220

期刊性質:國外

收錄於:SCI

審稿制度:

國別:CHE

出版型式:電子版